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Effect of Oliceridine on the Incidence of Postoperative Nausea and Vomiting (PONV) and Postoperative Recovery Quality in Hysteroscopic Surgery: A Prospective, Randomized, Double-Blind Controlled Study

Effect of Oliceridine on the Incidence of Postoperative Nausea and Vomiting (PONV) and Postoperative Recovery Quality in Hysteroscopic Surgery: A Prospective, Randomized, Double-Blind Controlled Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127113
Enrollment
Unknown
Registered
2026-06-24
Start date
2026-07-10
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative nausea and vomiting

Interventions

Control group:The suffentanyl group was induced by total anesthesia with suphentanyl 0.125ug/kg, propofol 2mg/kg, and cis atricoammmonium 0.15mg/kg. After full nitrogen removal and oxygenation, it was
Group Oliceridine:The Oliceridine group was induced by total anesthesia with 0.025mg/kg of Oliceridine, 2mg/kg of propofol, and 0.15mg/kg of cis-atrexamine. After full nitrogen removal and oxygenation

Sponsors

Lishui People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 65; 2. ASA (American Association of Anesthesiologists) grade I-II; 3. Patients and their families are aware of the contents and objectives of this study and voluntarily sign a written consent form.

Exclusion criteria

Exclusion criteria: 1. abnormal uterine or cervical anatomy, severe uterine adhesions are expected to cause serious trauma and complex operations with long operation time; 2. complicated cardiovascular or respiratory diseases; 3. diagnosis of serious heart, lung, liver or kidney diseases; 4. long-term smoking or alcohol history; 5. allergy to propofol, opioids or other anesthetic drugs; 6. history of alcohol or drug abuse; 7. preoperative severe anemia or intraoperative blood transfusion; 8. mental illness.

Design outcomes

Primary

MeasureTime frame
The incidence of Postoperative nausea and vomiting within 24 hours;

Secondary

MeasureTime frame
Quality of Recovery Score(QoR-40);The independent risk factors for postoperative nausea and vomiting after hysteroscopic surgery with oliceridine.;postoperative pain score;Postoperative comfort;The number of vasoactive drug administrations;The incidence of adverse reactions (e.g., respiratory depression, dizziness, pruritus, etc.).;Anesthesia recovery time;

Countries

China

Contacts

Public ContactJiang Jianxin

Lishui People's Hospital

1399815503@qq.com+86 189 5709 5806

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 3, 2026