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Discovery of Key Biomarkers for Colorectal Adenoma Based on Microbiomics and Construction of an Artificial Intelligence Risk Warning Model

Discovery of Key Biomarkers for Colorectal Adenoma Based on Microbiomics and Construction of an Artificial Intelligence Risk Warning Model

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600127081
Enrollment
Unknown
Registered
2026-06-24
Start date
2026-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Advanced adenoma group(AA):None
Non-progressive adenoma group(NAA):None
Advanced colorectal cancer group(CRC):None
Early colorectal cancer group(ERCR):None
Healthy control group:None

Sponsors

Ningbo First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Based on guidelines such as the "Colorectal Cancer Screening and Early Diagnosis and Treatment Plan (2024 Edition)" issued by the National Health Commission, the "Colorectal Cancer Diagnosis and Treatment Guidelines (2024)" issued by the Chinese Society of Clinical Oncology (CSCO), and the "Chinese Expert Consensus on Early Diagnosis and Treatment of Colorectal Cancer (2023 Edition)" issued by the Early Diagnosis and Treatment Group of the Oncology Branch of the Chinese Medical Association, inclusion criteria were established. Participants were selected for the corresponding groups based on the results of colonoscopy and pathological reports.

Exclusion criteria

Exclusion criteria: 1.Anal canal tumor, appendiceal tumor, neuroendocrine tumor, familial adenomatous polyposis; 2.Cases requiring additional surgery due to perforation or bleeding complications from endoscopic treatment; 3.Patients who have used antibiotics, glucocorticoids, or immunosuppressants within one month of sampling.

Design outcomes

Primary

MeasureTime frame
Intestinal histopathological results;

Secondary

MeasureTime frame
Blood Biochemistry;Digestive endoscopy findings;Tumor markers;

Countries

China

Contacts

Public ContactYuping Zhou

Ningbo First Hospital

nbuzhouyuping@126.com+86 15258127313

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 3, 2026