Coronary Artery Disease
Conditions
Interventions
Sponsors
Beijing Anzhen Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years; 2. Previous implantation of metallic stents (BMS or DES) and planned for coronary angiography; 3. Coronary angiography indicates in-stent restenosis (ISR): > 50% stenosis at the stent segment and the 5 mm margins proximal and distal; 4. Intraoperative IVUS/OCT integrated imaging can be completed (at the stent segment and the marginal segments proximal and distal); 5. Able to understand the research content and sign the informed consent form, and agree to complete 12-month follow-up and laboratory re-examination.
Exclusion criteria
Exclusion criteria: 1. For critical cases that require urgent treatment and do not allow additional imaging time (such as difficulties in maintaining hemodynamic stability, etc.); 2. For materials related to imaging examinations (such as contrast agents / flushing solutions) that are clearly contraindicated and cannot be replaced; 3. If the target lesion guide wire / catheter cannot pass or it is predicted that integrated machine imaging cannot be safely completed; 4. Other situations that the researcher deems unsuitable for inclusion (such as poor compliance, inability to complete follow-up, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ISR mechanism classification based on IVUS/OCT all-in-one machine and the composition spectrum of NA phenotypes (mechanical mechanism, NA stability phenotype, plaque burden, etc.); | — |
Secondary
| Measure | Time frame |
|---|---|
| Perioperative strategic decision-making changes based on intraluminal imaging mechanism information;The relationship between endovascular imaging mechanism phenotypes and clinical risk factors; | — |
Countries
China
Contacts
Public ContactZhang Min
Beijing Anzhen Hospital, Capital Medical University
Outcome results
None listed