Dentin Hypersensitivity, DH
Conditions
Interventions
Intervention Group:Brushing teeth with a placebo toothpaste following the Modified Bass brushing technique.
Sponsors
West China Hospital of Stomatology, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Healthy male or female subjects aged between 18 and 65 years (inclusive); 2. Subjects report sensitivity to cold, hot, sour, and sweet stimuli, pain when biting hard objects, rapid onset, sharp pain, and short duration. At least one tooth with dentin hypersensitivity is present, sensitive to tactile stimulation of 10g to 50g, and/or a cold air stimulation score of >=2; 3. The location of dentin hypersensitivity is the cervical area of the buccal surface, caused by wear or gingival recession. Visual or probing examination can clearly determine that the affected tooth has exposed dentin, no caries, no fillings, no tooth fractures, no cracks, no symptoms of pulpitis, and the clinical examination shows that the mobility of the sensitive tooth is less than I°; 4. Able to read, sign, and receive a copy of the signed informed consent form; 5. Willing and able to comply with the scheduled visit times, treatment plans, and other research procedures; 6. Not participating in other clinical trials during the trial period; 7. Agree not to use any non-trial toothpaste or mouthwash during the trial period. 8. Agree to postpone any non-emergency oral examinations, including teeth cleaning, until the end of the trial follow-up.
Exclusion criteria
Exclusion criteria: 1. The subjects have severe oral diseases, chronic diseases or a history of allergy to the test product; 2. They are in the progression stage of periodontal disease or have received periodontal treatment (including periodontal surgery) within the past year; 3. The mobility of sensitive teeth is greater than I°; 4. Teeth with large fillings or crowns, suspected pulpitis, caries, wedge-shaped defects, enamel cracks, or abutment teeth of removable partial dentures 5. They have a history of allergy or idiosyncratic reaction to oral hygiene products or their components; 6. They are allergic to toothpaste and its components; 7. Women who are pregnant or lactating; 8. They have used the following drugs within one month before participating in the study: anticonvulsants, antihistamines, antidepressants, sedatives, and tranquilizers; 9. They have used other anti-dentin hypersensitivity toothpaste; or are participating in other similar clinical trials at the same time; 10.There are any diseases or conditions that the researchers consider may affect the examination procedures and the safety of the subjects to complete the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Electronic pressure sensitive probing count ;Schiff cold air sensitivity index ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale ;Oral soft and hard tissue safety examination (OSHT); | — |
Countries
China
Contacts
Public ContactXian Liu
West China Hospital of Stomatology, Sichuan University
Outcome results
None listed