Periodontitis
Conditions
Interventions
Intervention Group:Conventional periodontal therapy combined with the use of Qinshen Qingrun Herbal Toothpaste for tooth brushing following the Modified Bass brushing technique.
Control Group:Conventional periodontal therapy combined with the use of a placebo toothpaste for tooth brushing following the Modified Bass brushing technique.
Sponsors
West China Hospital of Stomatology, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-65 years old, gender is not limited; 2. Diagnosed with stage I./II grade A/B periodontitis according to the 2018 new classification of periodontal disease; 3. At least 20 natural teeth are present in the mouth, and Ramfjord index teeth (i.e., 16 teeth, 21 teeth, 24 teeth, 36 teeth, 41 teeth, 44 teeth) are natural teeth, no missing and non-residual roots; 4. Have good vision, limb movement and judgment ability; 5. Voluntarily participate in the trial and sign the informed consent form, and be able to cooperate with the completion of the trial.
Exclusion criteria
Exclusion criteria: 1. Those who have a history of self-reported allergies to any of the ingredients used in this trial; 2. Pregnant and lactating women; 3. Those who have undergone periodontal treatment such as cleaning and scaling in the past 3 months; 4. Those who have used hormones, antibiotics and other drugs in the past 14 days; 5. Patients with liver impairment or renal insufficiency; 6. Abnormal thyroid function, blood diseases, acute viral stomatitis, traumatic ulcers, nervous system diseases, psychiatric diseases, etc.; 7. Participated in other clinical trials at the same time and did not meet the clinical endpoints, or participated in other clinical trials in the past 3 months; 8. Those who are unable to complete or cooperate with the test process.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding on probing (BOP); | — |
Secondary
| Measure | Time frame |
|---|---|
| Probing Pocket Depth (PPD);Gingivitis Index (GI); | — |
Countries
China
Contacts
Public ContactXian Liu
West China Hospital of Stomatology, Sichuan University
Outcome results
None listed