upper tract urothelial carcinoma
Conditions
Interventions
Test Group:Robot-assisted Autologous Renal Transplantation
Control Group:Robot-assisted Radical Nephroureterectomy
Sponsors
Beijing Miyun District Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Suspected ureteral carcinoma confirmed by at least one of the following examinations: contrast-enhanced abdominal CT and/or MRI, fluorescence in situ hybridization (FISH), or urinary cytology. 2. High-risk ureteral tumor with at least one of the following imaging or pathological features: hydronephrosis, tumor diameter >= 2 cm, high-grade cytology, high-grade ureteroscopic biopsy, multifocal lesions, or variant histology. 3. Ureteral tumor located at or below the iliac vessels, with no renal pelvic or proximal ureteral lesions identified on imaging. 4. Mild or moderate hydronephrosis of the affected kidney; glomerular filtration rate (GFR) > 15 mL/min, or preserved renal excretory function demonstrated on contrast-enhanced CT. 5. Voluntary participation with written informed consent obtained. 6. Age >= 18 years old.
Exclusion criteria
Exclusion criteria: 1. Impaired renal function of the affected kidney (GFR = II congestive heart failure, unstable symptomatic arrhythmia, or peripheral arterial disease Class >= II. 7. Pregnant or lactating women. 8. Severe atherosclerosis of the ipsilateral renal artery and external iliac artery precluding vascular anastomosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival (OS);2-year recurrence-free survival (RFS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in renal function;Intraoperative blood loss;Short-term surgical complications;Intraoperative cold ischemia time (CIT);Operative time;Intraoperative warm ischemia time (WIT);long-term surgical complications; | — |
Countries
China
Contacts
Public ContactCaiyong Lai
Beijing Miyun District Hospital
Outcome results
None listed