Sarcopenia
Conditions
Interventions
Experimental group:The experimental group was treated with probiotics (two bags a day)
Control group:The control group was given probiotics-free powder with the same appearance as probiotics.
Sponsors
Peking University People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 60 years; 2. Patients with sarcopenia meet the physical function assessment (gait speed < 1 m/s) and the measurement of DXA and BIA (male muscle mass < 7.0 kg/m^2 and female muscle mass < 5.7 kg/m^2); 3. Agree to participate in the experiment and cooperate with the visit, and sign the informed consent of the experiment.
Exclusion criteria
Exclusion criteria: 1. Chronic heart failure (NYHA III and IV), chronic kidney disease (CKD3-5 patients), chronic obstructive pulmonary disease (moderate and severe), neuromuscular diseases (ALS, SMA, inflammatory myopathy), rheumatoid arthritis, systemic lupus erythematosus and other CTD, long-term bed rest, post-stroke dyskinesia, long-term use of glucocorticoid, etc.; 2. Patients who have used antibiotics and/or probiotics in the past 4 weeks; 3. Patients who can't accept oral preparation treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skeletal muscle mass index of limbs; | — |
Secondary
| Measure | Time frame |
|---|---|
| Limb muscle mass;body fat percentage; | — |
Countries
China
Contacts
Public ContactYanan Wei
Peking University People's Hospital
Outcome results
None listed