Sepsis-Associated Encephalopathy (SAE)
Conditions
Interventions
SAE group (Sepsis-Associated Encephalopathy group) vs.Non-SAE group (Non-Sepsis-Associated Encephalopathy group):None
Sponsors
Chongqing University Three Gorges Hospital(Chongqing Three Gorges Central Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Aged >= 18 years, no gender restriction; 2.Initial diagnosis of sepsis conforming to the Sepsis-3 diagnostic criteria; 3.Expected ICU length of stay >= 72 hours; 4.The patient or their family member is informed and voluntarily signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Pregnant or breastfeeding women; 2.Presence of definite primary central nervous system diseases (e.g., stroke, intracranial tumor, intracranial infection, epilepsy, severe traumatic brain injury history); 3.History of severe cognitive impairment or psychiatric disorders; 4.Presence of malignancy or autoimmune diseases; 5.History of liver or kidney failure affecting consciousness; 6.Recent cardiopulmonary resuscitation; 7.Long-term alcoholism or drug abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of sepsis related encephalopathy;Non-invasive Multimodal Brain Function Monitoring;Serum Biomarkers;The area under the ROC curve (AUC), Sensitivity, Specificity; | — |
Countries
China
Contacts
Public ContactPengfei Pan
Chongqing University Three Gorges Hospital (Chongqing Three Gorges Central Hospital)
Outcome results
None listed