Schizophrenia
Conditions
Interventions
True stimulation group:Precision transcranial active stimulation targeting the left inferior parietal lobe
Sham stimulation group:Precision transcranial sham stimulation targeting the left inferior parietal lobe
Sponsors
Suzhou Guangji Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients with schizophrenia; 2. Male or female aged 18-60 years old; 3. Able to understand and sign the written informed consent form; 4. According to the DSM-5 clinical interview, it is determined that they meet the diagnostic criteria for schizophrenia; 5. MCCB visual learning and memory score <= 22 points.
Exclusion criteria
Exclusion criteria: 1. Clearly agitated and uncooperative; 2. Other Axis I mental disorders other than schizophrenia; 3. CDSS depression scale score >= 7 points; 4. Severe severity of suicidal tendency clinical overall assessment score > 3 points (moderate); 5. Alcohol abuse in the past 1 month, or substance abuse or substance dependence in the past 6 months; 6. Suffering from severe or unstable physical diseases, including: neurological diseases (delirium, dementia, stroke, epilepsy, migraine, etc.), congestive heart failure, angina pectoris, myocardial infarction, arrhythmia, hypertension (including untreated or uncontrollable hypertension), malignant tumors, immunocompromised subjects, and subjects with blood glucose higher than 12 mmol/L; 7. rTMS treatment, such as those with metal implants in the body; 8. Pregnant or lactating women; 9. Have claustrophobia and cannot undergo magnetic resonance scanning.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function score(MCCB);Gross functional score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive and Negative Symptom Scales; | — |
Countries
China
Contacts
Public ContactJunjie Wang
Suzhou Guangji Hospital
Outcome results
None listed