Chronic periodontitis (Stage III/IV) with vertical bone resorption
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Age 35-70 years, regardless of gender; (2) Patients with stage III/IV periodontitis who have undergone conventional periodontal basic treatment for 3 months; (3) Probing depth (PD) at the periodontal defect site is greater than 5mm; (4) Periodontal attachment level (AL) at the defect site: Gingival recession level at the periodontal defect site, using the cementoenamel junction (CEJ) as a reference line, with a distance =4mm from the CEJ; (5) CBCT shows vertical bone resorption; (6) The periodontal defect site is a two- or three-wall infrabony pocket with a defect depth greater than 2mm; (7) Full-mouth plaque score and bleeding score are each below 30%.
Exclusion criteria
Exclusion criteria: (1) Blood pressure of hypertensive patients within 1 month before surgery: systolic blood pressure >200 mmHg or diastolic blood pressure >115 mmHg; (2) Patients with systemic diseases (malignant tumors, heart failure due to cardiac disease, myocardial infarction within the past 6 months;angina symptoms within the past 6 months); (3) Patients who have undergone surgical treatment at the periodontal defect site or adjacent periodontal tissues; (4) Patients with more than two-thirds of the bone wall missing on either side of the periodontal defect at the treatment site; (5) Patients with severe periodontal disease (alveolar bone resorption exceeding two-thirds of the root length); (6) Patients with severe bleeding tendency or coagulation dysfunction (white blood cell count WBC <3.0×10^9/L or platelet count PLT <60×10^9/L); (7) Patients with mental or intellectual disabilities; (8) Pregnant or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in periodontal defect height; | — |
Secondary
| Measure | Time frame |
|---|---|
| Periodontal attachment level (AL); | — |
Countries
China
Contacts
Beijing Stomatological Hospital , Capital Medical University