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Clinical Study of M-MINST Combined with Periodontal Endoscope in the Treatment of Periodontitis with Vertical Bone Resorption

Clinical Study of M-MINST Combined with Periodontal Endoscope in the Treatment of Periodontitis with Vertical Bone Resorption

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600126958
Enrollment
Unknown
Registered
2026-06-22
Start date
2026-06-22
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic periodontitis (Stage III/IV) with vertical bone resorption

Interventions

M-MINST Combined Periodontal Endoscopy Treatment Group:Modified Minimally Invasive Non-Surgical Therapy (M-MINST) combined with periodontal endoscopy
Traditional scaling and root planing (SRP) combined with periodontal endoscopy group:Traditional scaling and root planing (SRP) combined with periodontal endoscopy

Sponsors

Beijing Stomatological Hospital , Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Age 35-70 years, regardless of gender; (2) Patients with stage III/IV periodontitis who have undergone conventional periodontal basic treatment for 3 months; (3) Probing depth (PD) at the periodontal defect site is greater than 5mm; (4) Periodontal attachment level (AL) at the defect site: Gingival recession level at the periodontal defect site, using the cementoenamel junction (CEJ) as a reference line, with a distance =4mm from the CEJ; (5) CBCT shows vertical bone resorption; (6) The periodontal defect site is a two- or three-wall infrabony pocket with a defect depth greater than 2mm; (7) Full-mouth plaque score and bleeding score are each below 30%.

Exclusion criteria

Exclusion criteria: (1) Blood pressure of hypertensive patients within 1 month before surgery: systolic blood pressure >200 mmHg or diastolic blood pressure >115 mmHg; (2) Patients with systemic diseases (malignant tumors, heart failure due to cardiac disease, myocardial infarction within the past 6 months;angina symptoms within the past 6 months); (3) Patients who have undergone surgical treatment at the periodontal defect site or adjacent periodontal tissues; (4) Patients with more than two-thirds of the bone wall missing on either side of the periodontal defect at the treatment site; (5) Patients with severe periodontal disease (alveolar bone resorption exceeding two-thirds of the root length); (6) Patients with severe bleeding tendency or coagulation dysfunction (white blood cell count WBC <3.0×10^9/L or platelet count PLT <60×10^9/L); (7) Patients with mental or intellectual disabilities; (8) Pregnant or breastfeeding women.

Design outcomes

Primary

MeasureTime frame
Changes in periodontal defect height;

Secondary

MeasureTime frame
Periodontal attachment level (AL);

Countries

China

Contacts

Public ContactZhenhua Luo

Beijing Stomatological Hospital , Capital Medical University

laryhua@163.com+86 105 7099499

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 3, 2026