Traumatic Brain Injury (TBI)/Non-Traumatic Brain Injury (Non-TBI)
Conditions
Interventions
Traumatic Brain Injury group (TBI group) vs. Non-Traumatic Brain Injury group (non-TBI group):Etiology (TBI vs. non-TBI)
Sponsors
Shandong Rehabilitation Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Meets the diagnostic criteria for Minimally Conscious State (MCS), with a Coma Recovery Scale-Revised (CRS-R) score between 6 and 10 at admission (or diagnosed as MCS- or MCS+ according to established criteria). E; 2.Etiology is clearly identified as Traumatic Brain Injury (TBI) or non-TBI (including Hypoxic-Ischemic Encephalopathy [HIE] and Cerebrovascular Disease [CVD]). 3.Aged >= 18 years. 4.Time from onset to enrollment (disease duration) <= 3 months. 5.Complete baseline data and at least 3 months of follow-up data are available.
Exclusion criteria
Exclusion criteria: 1.A history of severe neurological diseases requiring long-term treatment with medications such as amantadine, levodopa, or other similar agents (e.g., Alzheimer's disease, Parkinson's disease, etc.). 2.Presence of severe complications that may interfere with CRS-R assessment (e.g., uncontrolled epilepsy, severe infections, etc.). 3.Incomplete medical records with a missing data rate of >20% for key variables.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the 3-month rate of consciousness recovery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional outcome; | — |
Countries
China
Contacts
Public ContactXu Weiwei
Shandong Rehabilitation Hospital
Outcome results
None listed