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Research on the Coupled Neural Mechanism and Rehabilitation Prediction of Language-Executive Network in Post-stroke Aphasia

Research on the Coupled Neural Mechanism and Rehabilitation Prediction of Language-Executive Network in Post-stroke Aphasia

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600126910
Enrollment
Unknown
Registered
2026-06-18
Start date
2026-06-22
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke aphasia

Interventions

Post-stroke aphasia patient group:none
The group of non-aquaphobia patients after stroke:none

Sponsors

Wuxi Mental Health Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Inclusion criteria for the PSA group: (1) First or recurrent left hemisphere ischemic or hemorrhagic stroke, confirmed by MRI/CT; (2) Duration of disease 1-12 months (subacute to early chronic), with initial assessment completed during hospitalization or outpatient visits; (3) WAB-AQ = 6 years of education; (5) Basic ability to cooperate in completing fNIRS acquisition and behavioral tasks (with the aid of auxiliary prompts). 2. Inclusion criteria for the PSnA group: (1) Confirmed diagnosis of stroke (left or right hemisphere), confirmed by imaging; (2) WAB-AQ >= 93.8, normal language screening; (3) Age-matched (+/- 5 years), education-matched (+/- 3 years), and disease duration-matched (+/- 4 weeks) with the PSA group.

Exclusion criteria

Exclusion criteria: 1. Severe consciousness impairment, MMSE = 15; 4. fNIRS contraindications: scalp lesions > 30%, effective channels < 70%.

Design outcomes

Primary

MeasureTime frame
Language function;Resting-state functional connectivity;

Secondary

MeasureTime frame
Eriksen flanker task;Vocabulary proficiency;Total Score of Language Comprehension Load;

Countries

China

Contacts

Public ContactFang Hui

Wuxi Mental Health Center

fanghui112346@163.com+86 510 8321 9650

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 29, 2026