1. Atherosclerosis
Conditions
Interventions
Control group (iodinated contrast medium group)::None
Gadolinium contrast agent group:None
Sponsors
Xi'an Daxing Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Inclusion Criteria for Gadolinium-Based Contrast Agent Group: (1) Aged 18 years or older; (2) Requiring CTA scanning based on clinical conditions to evaluate one of the following diseases: atherosclerosis, vascular stenosis or occlusion, aortic dissection, pulmonary embolism, and other vascular-related disorders; (3) Patients unsuitable for iodine-based contrast agents due to iodine allergy or severe allergic history, requiring multiple re-examinations after interventional therapy, or renal insufficiency (eGFR 30-60 mL/min/1.73 m^2); (4) Complete imaging data with image quality meeting the minimum diagnostic requirements. 2. Inclusion Criteria for Control Group: (1) Aged 18 years or older; (2) Requiring CTA scanning based on clinical conditions to evaluate one of the following diseases: atherosclerosis, vascular stenosis or occlusion, aortic dissection, pulmonary embolism, and other vascular-related disorders; (3) Complete imaging data with image quality meeting the minimum diagnostic requirements.
Exclusion criteria
Exclusion criteria: 1. Inclusion Criteria for Gadolinium-Based Contrast Agent Group: (1) Aged 18 years or older; (2) Requiring CTA scanning based on clinical conditions to evaluate one of the following diseases: atherosclerosis, vascular stenosis or occlusion, aortic dissection, pulmonary embolism, and other vascular-related disorders; (3) Patients unsuitable for iodine-based contrast agents due to iodine allergy or severe allergic history, requiring multiple re-examinations after interventional therapy, or renal insufficiency (eGFR 30-60 mL/min/1.73 m^2); (4) Complete imaging data with image quality meeting the minimum diagnostic requirements. 2. Exclusion Criteria for Control Group: (1) Known allergy to iodinated contrast media or its components; (2) Severe renal insufficiency (eGFR < 30 mL/min/1.73 m^2); (3) Previously diagnosed nephrogenic systemic fibrosis (NSF); (4) Pregnant or lactating women; (5) Severe cardiopulmonary dysfunction precluding tolerance to scanning; (6) Inability to cooperate with scanning (e.g., severe claustrophobia or failure to remain motionless); (7) Severe neurological disorders (e.g., epilepsy, Parkinson's disease, etc.) that may compromise image quality.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Image Quality Assessment;Mean attenuation value of the image; | — |
Secondary
| Measure | Time frame |
|---|---|
| Signal to Noise Ratio;Contrast-to-Noise Ratio; | — |
Countries
China
Contacts
Public ContactYue Qin
Xi'an Daxing Hospital
Outcome results
None listed