Osteoporosis, sarcopenia, osteoarthritis
Conditions
Interventions
Yili Xinhuo Nourishing Bone Milk Powder Set:Yili Xinhuo Nourishing Bone Milk Powder
Blank control group:None
Sponsors
Nutrition and Health Institute, Chinese Center for Disease Control and Prevention
Eligibility
Sex/Gender
All
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Aged 40-60 years, women are postmenopausal; 2.routine physical examination is normal; 3.no significant change in body weight in the past 6 months; 4.body mass index (BMI) in the range of 18.5-27.9 kg/m^2;
Exclusion criteria
Exclusion criteria: 1.Lactose intolerance or dairy allergy; 2.Suffering from malignant tumors, diabetes, digestive system diseases, liver and kidney dysfunction, or other diseases affecting protein and amino acid digestion and absorption; 3.Pregnant or breastfeeding women; 4.History of surgery in the past three months; 5.People who consume excessive alcohol or smoke;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Calf circumference, grip strength, 6-meter walking speed, chair stand test, skeletal muscle mass;N-MID OC?PINP?B-ALP?CITP?-5bTRAP-5b; | — |
Secondary
| Measure | Time frame |
|---|---|
| IL-6?TNF-a?IL-1ß?IL-10?IL-4;SCFAs,Fecal short-chain fatty acids;Parathyroid hormone, calcitonin;Blood calcium concentration, blood phosphorus concentration;Bone density;Gut microbiota;uCTX-II? COMP;Body weight and body composition; | — |
Countries
China
Contacts
Public ContactLi Min
Nutrition and Health Institute, Chinese Center for Disease Control and Prevention
Outcome results
None listed