female infertility
Conditions
Interventions
Painless oocyte retrieval group:None
Non-anesthetic oocyte retrieval group:None
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 45 years; 2.Underwent transvaginal ultrasound-guided oocyte retrieval at our center; 3.The analgesia/anesthesia method on the day of oocyte retrieval was clearly documented and could be classified as either the painless oocyte retrieval group or the non-anesthetic oocyte retrieval group; 4.Availability of complete or substantially complete follow-up data, including oocyte retrieval data, oocyte quality assessment, embryo development assessment, and clinical pregnancy outcomes; 5.Patient clinical data could be retrieved through the hospital electronic medical record system, reproductive medicine database, surgical anesthesia system, and other relevant sources.
Exclusion criteria
Exclusion criteria: 1. Incomplete data or missing key variables: inability to determine the analgesia/anesthesia method used during oocyte retrieval;missing key outcome data, including the number of oocytes retrieved, oocyte quality, embryo development data, clinical pregnancy outcomes, etc.or inability to retrieve records from the electronic medical record system, anesthesia records, or reproductive medicine database; 2. Severe complications affecting outcomes: occurrence of serious intraoperative complications during oocyte retrieval, such as failed ovarian puncture or major intraoperative bleeding; 3. Use of non-standard anesthesia/analgesia protocols during oocyte retrieval, making it difficult to classify patients into either the painless oocyte retrieval group or the non-anesthetic oocyte retrieval group.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of neonatal or embryo adverse events; | — |
Secondary
| Measure | Time frame |
|---|---|
| oocyte retrieval rate;Abnormal rate of neonatal disease screening;Type of embryo transfer;Available blastocyst number;retrieved oocyte number;abortion ratio;The number and rate of embryo cleavage;The rate of MII oocyte;The number and rate of Normal fertilization;oocyte morphology;premature delivery rate;clinical pregnancy rate;birth weight;ongoing pregnancy rate;biochemical pregnancy rate;the rate of neonatal congenital malformation;The number and rate of high-quality embryos;The number of MII oocyte;The number and rate of blastulation; | — |
Countries
China
Contacts
Public ContactRen Li
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed