Primary knee osteoarthritis
Conditions
Interventions
Observation group:None
Sponsors
Xiangshan Hospital of Traditional Chinese Medicine, Huangpu District,Shanghai
Eligibility
Sex/Gender
All
Age
65 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age 65-75 years; 2. Meets the diagnosis for knee osteoarthritis, which can be judged based on clinical symptoms, signs, and existing imaging data; if there’s knee X-ray data, record the Kellgren-Lawrence (KL) grade as a baseline severity indicator; 3. Able to complete baseline assessments for symptoms, function, sarcopenia-related indicators, and obesity-related indicators, and is willing to participate in long-term follow-up; 4. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Neurological disease, severe cardiopulmonary disease, malignancy, or other severe systemic diseases that substantially affect gait, muscle function, or functional assessment. 2. Previous severe lower-limb trauma, surgery, or other disorders that may substantially influence gait or physical function. 3. Inability to complete core assessments, including WOMAC, knee pain score, handgrip strength, gait speed, timed up-and-go test, or body composition assessment. 4. Severe missing baseline data that cannot be supplemented. 5. Any other condition judged by the investigators to be unsuitable for long-term cohort participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WOMAC total score-defined symptom progression at 12 months; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in WOMAC total score;Handgrip strength;Gait speed;Knee pain visual analog scale;Outcome: Timed up-and-go test;Important clinical events during follow-up; | — |
Countries
China
Contacts
Public ContactGuangming Liu
Xiangshan Hospital of Traditional Chinese Medicine, Huangpu District,Shanghai
Outcome results
None listed