Anti-fatigue ability
Conditions
Interventions
Intermittent hypoxic training (IHT):Participants in the intermittent hypoxic training (IHT) group were exposed to a hypobaric hypoxic environment equivalent to an altitude of 4000 m, established using
Normobaric normoxic control (NNC):Participants in the normobaric normoxic control (NNC) group were exposed to a normobaric normoxic environment (ambient air) under identical conditions. The interventi
Sponsors
The First Affiliated Hospital of Air Force Military Medical University
Eligibility
Sex/Gender
Male
Age
22 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. Healthy males aged 22–35 years, with a body mass index (BMI) between 19 kg/m^2 and 28 kg/m^2 (inclusive); 2. Bilateral isokinetic peak torque values > 120 Nm on three consecutive 30-second bouts of isokinetic leg press testing; 3. Residing permanently at an altitude < 1000 m above sea level; 4. No use of any medications within 1 month prior to enrollment; 5. Provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. History of travel or residence at high altitude (> 2500 m) within the past 2 years (any exposure qualifies); 2. Presence of any of the following conditions: cardiovascular or cerebrovascular diseases, asthma, upper respiratory tract infection, anemia, decompression sickness, or obstructive sleep apnea-hypopnea syndrome (OSAHS); 3. Acute or chronic injury to the lumbar spine, knee joint, or ankle joint.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rating of perceived exertion (RPE); | — |
Secondary
| Measure | Time frame |
|---|---|
| Numerical rating scale (NRS);Karolinska sleepiness scale (KSS);Functional near-infrared spectroscopy (fNIRS);Paired-pulse transcranial magnetic stimulation (ppTMS);Cardiopulmonary exercise testing (CPET);Psychomotor vigilance task (PVT);Near-infrared brain functional imaging;Paired transcranial magnetic stimulation; | — |
Countries
China
Contacts
Public ContactYuan Hua
The First Affiliated Hospital of Air Force Military Medical University
Outcome results
None listed