Pulmonary Space-Occupying Lesion
Conditions
Interventions
Esketamine exposure group (E group):None
Non-exposure group (C group):None
Sponsors
Suining Central Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age >=65 years; 2. BMI 18–30 kg/m^2; 3. ASA class I–III; 4. First elective thoracoscopic surgery; 5. Complete clinical examinations including routine blood tests and biochemistry; 6. Patients receiving ultrasound-guided serratus anterior plane block.
Exclusion criteria
Exclusion criteria: 1. Allergy to any drug or component used in this study; 2. Coagulation dysfunction or ongoing anticoagulant therapy; 3. Infection at the puncture site; 4. Pre-existing cognitive impairment or mental disorder; 5. History of ketamine or opioid dependence; 6. Severe valvular heart disease, severe arrhythmias, or liver/kidney dysfunction; 7. Patients with poorly controlled or untreated hypertension; 8. Patients with untreated or inadequately treated hyperthyroidism.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Quality of Recovery (QoR-15 score); | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale;Sufentanil consumption;Remifentanil consumption;Extubation time;PACU length of stay;Time to first ambulation;Time to first oral intake;Sleep quality;Postoperative hospital stay;Pulmonary complications;Analgesic pump infusion dose;Frequency and total dose of rescue analgesia; | — |
Countries
China
Contacts
Public ContactLu Hai
Suining Central Hospital
Outcome results
None listed