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Research on the Neuromodulation Mechanism of TI Intervention in Elderly Cognitive Impairment (Memory Impairment)

Research on the Neuromodulation Mechanism of TI Intervention in Elderly Cognitive Impairment (Memory Impairment)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600126873
Enrollment
Unknown
Registered
2026-06-17
Start date
2026-06-17
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CognitiveImpairment

Interventions

Time-interference Transcranial Electrical Stimulation Therapy:temporal inference stimulation
sham inference stimulation:sham inference stimulation

Sponsors

Jiangsu Province Geriatric Hospital(Geriatric Hospital of Naning Medical University, Jiangsu Province Official Hospital, Jiangsu Province Geriatric Hospital Telehealth Services)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 60-80 who have abnormal results on cognitive impairment screening tests show memory problems on the Wechsler Memory Scale (WMS); 2. Head MRI and other imaging tests didn't find any issues that would affect cognitive impairment treatment; 3. Condition is stable, complications are well controlled, and there are no contraindications for cognitive impairment treatment or issues that would interfere with clinical evaluation.

Exclusion criteria

Exclusion criteria: 1. Past major neurological diseases (epilepsy, dementia, Parkinson's disease); 2. Serious heart or respiratory diseases; 3. Severe liver or kidney dysfunction; 4. Intracranial metal implants; 5. Active bleeding or blood clotting disorders.

Design outcomes

Primary

MeasureTime frame
RAVLT delayed recall;

Secondary

MeasureTime frame
DTI fractional anisotropy (FA) values;resting state fMRI (ReHo functional connectivity);?-? PAC strength;

Countries

China

Contacts

Public ContactHua Xu

Jiangsu Province Geriatric Hospital(Geriatric Hospital of Naning Medical University, Jiangsu Province Official Hospital, Jiangsu Province Geriatric Hospital Telehealth Services)

miqimama1234@163.com+86 25 8331 1721

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 29, 2026