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Cardiac Rehabilitation to Improve Post-Exercise Blood Pressure Recovery in Elderly Patients with Stable Angina

Effect of Standardized Cardiac Rehabilitation on Delayed Post-Exercise Blood Pressure Recovery in Elderly Patients with Stable Angina and Development of a Response Index: A Single-Arm Interventional Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600126837
Enrollment
Unknown
Registered
2026-06-17
Start date
2026-06-30
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stable angina pectoris (CCS grade I-II) with delayed post-exercise blood pressure recovery (SBPRR3 > 0.90)

Interventions

Standardized Cardiac Rehabilitation Group:Standardized Cardiac Rehabilitation

Sponsors

Shanghai Geriatric Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age =65 years; 2.Confirmed delayed post-exercise blood pressure recovery by cardiopulmonary exercise testing (SBPRR3 > 0.90); 3.Diagnosis of stable angina pectoris, CCS grade I-II; 4.NYHA functional class I-II; 5.Voluntarily sign informed consent.

Exclusion criteria

Exclusion criteria: 1.Acute coronary syndrome, acute myocardial infarction, stroke or transient ischemic attack within the past 3 months; 2.Decompensated heart failure, uncontrolled severe arrhythmia, severe valvular heart disease, obstructive hypertrophic cardiomyopathy, acute myocarditis or pericarditis; 3.Inability to complete exercise testing and training due to musculoskeletal, neurological, peripheral vascular or severe COPD; 4.Resting systolic blood pressure =180 mmHg and/or diastolic blood pressure =110 mmHg; 5.Severe liver or kidney dysfunction or malignancy; 6.Cognitive impairment or mental disorder that precludes compliance with assessment and intervention.

Design outcomes

Primary

MeasureTime frame
Change in SBPRR? (?SBPRR?);

Secondary

MeasureTime frame
Change in 6-minute walk distance (?6MWD);Incidence of adverse events;Change in E/e' ratio (?E/e');Proportion of subjects with normalized SBPRR? (=0.90) after intervention;Change in 30-second chair stand test (?30s-ST);Change in Patient Health Questionnaire-9 score (?PHQ-9);Change in International Classification of Functioning, Disability and Health (ICF) score (?ICF);Change in Generalized Anxiety Disorder-7 score (?GAD-7);Change in peak oxygen uptake (?peak VO?);

Countries

China

Contacts

Public ContactZhang Di

Shanghai Geriatric Medical Center

zhang.di@zsgmc.sh.cn+86 21 3111 8098

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 29, 2026