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Application of Abdominal Compression in the Prevention of Hypoxemia in Patients Undergoing Comfort-Oriented Gastrointestinal Endoscopy: A Prospective, Dual-Center, Randomized Controlled Trial

Application of Abdominal Compression in the Prevention of Hypoxemia in Patients Undergoing Comfort-Oriented Gastrointestinal Endoscopy: A Prospective, Dual-Center, Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600126826
Enrollment
Unknown
Registered
2026-06-16
Start date
2026-06-30
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypoxemia

Interventions

MMAC group:Modified Manual Abdominal Compression
Sham group:Routine management (oxygen via nasal cannula at 3 L/min)

Sponsors

The First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age 18–80 years; 2. Scheduled for elective gastrointestinal endoscopy; 3. American Society of Anesthesiologists (ASA) physical status classification I–III; 4. Voluntarily signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Contraindications to abdominal compression (e.g., pyloric obstruction, reflux esophagitis, abdominal wall hernia, recent abdominal surgery, or severe ascites); 2. Baseline SpO2 < 95%; 3. Severe cardiopulmonary, hepatic, or renal dysfunction; 4. Pregnancy or lactation; 5. Emergency endoscopy; 6. Allergy to propofol, eggs, soybean, or albumin. 7. Other conditions that, in the opinion of the investigator, would make the subject unsuitable for participation in the study.

Design outcomes

Primary

MeasureTime frame
The incidence of SpO2 < 90%;

Secondary

MeasureTime frame
diaphragmatic excursion;Area under the curve for SpO2 < 95%,;Rate of endoscopy interruption/scope withdrawal;

Countries

China

Contacts

Public ContactGuangchao Zhang

The First Affiliated Hospital of Soochow University

gz90_09@163.com+86 512 6797 2861

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 29, 2026