Coronary disease
Conditions
Interventions
Volume-controlled ventilation (VCV) group:Use the VCV mode
pressure controlled ventilation-volume guaranteed group:Select the PCV-VG mode
Sponsors
General Hospital of Ningxia Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age: 40 - 65 years old, gender not restricted; 2. Body Mass Index (BMI) within the normal range (18.5 - 27.9 kg/m^2); 3. American Society of Anesthesiologists (ASA) classification: III - IV grade; 4. Three-vessel coronary artery disease with the bypass surgery sequence uniformly being: anterior descending branch ? right coronary artery ? circumflex branch; 5. Preoperative New York Heart Association (NYHA) cardiac function classification: II - III grade; 6. Preoperative laboratory tests showed that liver, kidney functions and coagulation functions were basically normal.
Exclusion criteria
Exclusion criteria: 1. Those who refused to sign the informed consent form; 2. Left ventricular ejection fraction (LVEF) < 40%; 3. Those who failed in percutaneous coronary intervention and needed emergency surgery; 4. Those who died during the operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate;Mean Arterial Pressure;Central venous pressure;Cardiac output;Cardiac index;Stroke volume;Stroke volume variability; | — |
Secondary
| Measure | Time frame |
|---|---|
| Arterial blood gas analysis parameters;Anesthesia duration;Surgical duration;Intraoperative fluid infusion volume;Blood loss;Urine volume;The use of vasoactive drugs during changes in body position; | — |
Countries
China
Contacts
Public ContactWei Xiaoyong
General Hospital of Ningxia Medical University
Outcome results
None listed