Coronary Atherosclerotic Heart Disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old; 2. Have completed more than 6 years of education; 3. Patients with coronary heart disease who plan to undergo elective coronary artery bypass grafting (CABG); 4. Have at least 5 days of preoperative preparation time before the surgery; 5. Agree to undergo cognitive function tests and cognitive training and are able to follow the requirements for follow-up.assessments.
Exclusion criteria
Exclusion criteria: 1. Previously diagnosed with dementia or with a Mini-Mental State Examination (MMSE) score of less than 22; 2. Had a history of delirium; 3. Caused by cognitive dysfunction resulting from neurological and psychiatric disorders such as head trauma, brain tumors, stroke, Parkinson's disease, schizophrenia, Alzheimer's disease, anxiety disorder, depression, etc.; 4. Has blindness, deafness, or other reasons preventing normal communication or using cognitive training equipment; 5. Heavy drinking or taking drugs that affect cognitive function (antihistamines, antipsychotics, etc.); 6. Unable to master the use of cognitive training equipment after 2 training sessions, each lasting 30 minutes; 7. Severe liver or kidney dysfunction or critically ill condition with extremely poor prognosis, expected survival period less than 1 month; 8. Previously undergone neurosurgery or had a history of head tumors; 9. Patients with atrial fibrillation, structural heart disease, or infectious endocarditis; 10. Patients who received other surgeries in addition to CABG; 11. Patients currently participating in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Cognitive Dysfunction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Major Adverse Cardiovascular Events (MACE);Basic Cognitive Ability Test;Score of the Five-Level Five-Dimensional Health Scale;Simple Intelligence Status Examination Scale score;Montreal Cognitive Assessment; | — |
Countries
China
Contacts
Beijing Anzhen Hospital Affiliated to Capital Medical University.