Cerebral small vessel disease
Conditions
Interventions
The group with adequate serum 25(OH)D levels:None
Group with insufficient serum 25(OH)D levels:None
Group with deficiency of serum 25(OH)D level:None
Sponsors
The First Affiliated Hospital of University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18 - 80 years old; 2.The brain MRI imaging shows any of the following imaging markers of CSVD: lacunar infarction, white matter hyperintensity, cerebral microbleeds, or enlarged perivascular spaces. 3.The patient or his legal representative voluntarily participates in the study and signs the informed consent form;
Exclusion criteria
Exclusion criteria: 1.A history of dementia; 2.A history of mental disorders or current treatment for mental illnesses, such as taking anxiolytics, antidepressants, mood stabilizers, antipsychotics and other drugs that may interfere with the assessment; 3.A history of drug abuse or dependence; 4.Pregnant women; 5.Severe physical illnesses that may interfere with the assessment; 6.Contraindication to MRI scan; 7.Declining to participate;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total MRI burden of cerebral small vessel disease;Scores of MoCA scale;The volumes of different brain regions and cortical thickness; | — |
Countries
China
Contacts
Public ContactJieping Lu
The First Affiliated Hospital of University of Science and Technology of China
Outcome results
None listed