Systemic Lupus Erythematosus
Conditions
Interventions
Case series:None
Sponsors
Renji Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
14 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Male or female aged 14–85 years. 2. Diagnosed with SLE meeting any one of the following criteria: 1997 American College of Rheumatology (ACR) classification criteria 2012 Systemic Lupus International Collaborating Clinics (SLICC) classification criteria 2019 European Alliance of Associations for Rheumatology/American College of Rheumatology (EULAR/ACR) classification criteria 3. Previously tested positive for ANA, anti-dsDNA, or anti-Sm antibodies. 4. Presence of active, biopsy-proven lupus nephritis according to the 2003 ISN/RPS classification criteria.
Exclusion criteria
Exclusion criteria: 1. Pathological specimen inadequate for diagnosis. 2. Concomitant other severe renal diseases (e.g., diabetic nephropathy, chronic kidney disease, etc.). 3. Explicit refusal to participate in the study (prospective component).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SLEDAI – 2000;PGA;LLDAS;24-hour urine protein;Creatinine;eGFR;C3;C4;Anti-dsDNA; | — |
Secondary
| Measure | Time frame |
|---|---|
| Immunoglobulin (IgG/A/M);ANA;Anti-ENA;antiphospholipid antibody;SDI;DORIS ; | — |
Countries
China
Contacts
Public ContactDing Huihua
Renji Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed