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Investigation of the Regulatory Mechanisms of Hepatic Glucose and Lipid Homeostasis by Different GCKR Transcripts

Investigation of the Regulatory Mechanisms of Hepatic Glucose and Lipid Homeostasis by Different GCKR Transcripts

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600126756
Enrollment
Unknown
Registered
2026-06-15
Start date
2026-06-16
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes

Interventions

Normal liver tissue group (diabetic and non-diabetic subgroups):None
Fatty liver tissue group (diabetic and non-diabetic subgroups):None
Hepatic malignant tumor tissue group (diabetic and non-diabetic subgroups):None
Cirrhotic liver tissue group (diabetic and non-diabetic subgroups):None
Other tumor tissues (e.g., pancreatic tumor, pancreatic stone, duodenal ampullary tumor):None

Sponsors

The Second Xiangya Hospital of Central South University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1: Patients scheduled to undergo partial hepatectomy at this center due to their own medical condition 2: No medical or anesthesia contraindications for surgery 3: Understand the nature of the study procedures, willing to participate, and provide written informed consent

Exclusion criteria

Exclusion criteria: 1: Patients with other severe comorbidities: severe renal insufficiency, cardiovascular diseases, or other serious medical conditions 2: Patients who have received preoperative treatments such as radiotherapy, chemotherapy, immunotherapy, or targeted therapy 3: Long-term use of immunosuppressants, hormonal medications, etc. 4: Active viral hepatitis

Design outcomes

Primary

MeasureTime frame
Blood glucose;Glycated Hemoglobin (HbA1c);Lipid Profile;Liver Lesions;Body mass index;ALT;AST;Albumin;Total Bilirubin;

Secondary

MeasureTime frame
Complete blood count ;Creatinine;Uric Acid;

Countries

China

Contacts

Public ContactHou-De Zhou;Hui-Xuan Wu

The Second Xiangya Hospital of Central South University

houdezhou@csu.edu.cn+86 731 8529 2150

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 29, 2026