Osteoporotic fragility fracture
Conditions
Interventions
Case series :None
Sponsors
Yuebei People’s Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients who have completed lumbar and hip bone density testing during hospitalization and have been diagnosed with osteoporosis; 2. Patients with a clear history of low-energy injury exposure; 3. Patients with complete clinical data (height, weight, gender, age), relevant biochemical tests (such as red blood cell distribution width (SD), monocyte percentage), and bone density data with a completeness rate of >=70% (meeting data cleaning requirements);
Exclusion criteria
Exclusion criteria: 1. Exclusion of fracture types (non-fragile fractures) High-energy trauma fractures: fractures caused by car accidents, falls from heights, heavy object injuries, etc. Pathological fractures: secondary osteoporosis caused by bone tumors, metastatic cancer of the bone, multiple myeloma, Paget's disease, bone tuberculosis, etc. Fragility Fracture Secondary to Osteoporosis: Fractures due to long-term hormone therapy (>=3 months), hyperparathyroidism, Cushing's syndrome, chronic kidney/liver disease, rheumatoid arthritis, etc. with clear secondary factors. 2. Exclusion of underlying diseases and conditions Severe heart, lung, liver, and kidney failure, advanced malignant tumors, expected survival <12 months, mental illness, cognitive impairment, long-term bedridden/paralysis. 3. Data and study feasibility Exclusion of clinical data with severe missingness (core variables: age, gender, bone density, fracture history, missing key medications), loss to follow-up, data falsification/outliers that cannot be corrected, and participation in other clinical intervention trials that interfere with this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Laboratory biochemical testing indicators;;Drug exposure measurement indicators;Clinical history collection indicators;Quantitative bone density measurement indicators;Anthropometric indicators; | — |
Countries
China
Contacts
Public ContactSi Zebing
Yuebei People’s Hospital
Outcome results
None listed