Periodontal disease
Conditions
Interventions
Gold Standard:The diagnostic results made by six experts with associate senior professional titles or above in periodontology, based on the new international classification of periodontal diseases rel
Sponsors
Peking University Hospital of Stomatology
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Able to understand the research content and cooperate in signing the informed consent form. 2. Inclusion criteria for periodontal health volunteers: sites with probing bleeding =10%, probing depth =5 mm; radiographic bone loss up to the middle third of the root or more; teeth lost due to periodontitis =6 mm, vertical bone loss >=3 mm, furcation involvement degree II or III, moderate alveolar ridge defects. 8. Periodontal disease subgrouping: E, Stage IV periodontitis: the site with the worst interproximal CAL is >=5 mm; radiographic bone loss up to the middle third of the root or more; teeth lost due to periodontitis >=5; in addition to meeting the complexity criteria of Stage III, at least one of the following complexity adjustment factors must be present: impaired masticatory function, secondary trauma (tooth mobility >=2), severe alveolar ridge defects, occlusal disorders, misalignment, scattered gaps, fewer than 20 remaining teeth (10 functional pairs).
Exclusion criteria
Exclusion criteria: 1.Confirmed history of hepatitis B, tuberculosis, hepatitis C, syphilis, HIV infection, etc. 2.Pregnant or breastfeeding women. 3.Received periodontal treatment (basic periodontal therapy or surgical treatment) within the previous 6 months. 4.Taken specific medications (e.g., anticoagulants, hormones, antibiotics) within the previous 3 months. 5.Received orthodontic or orthognathic surgery. 6.History of bisphosphonate use or head and neck radiotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Probing Depth, PD;Sensitivity;Specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical attachment loss,CAL;Plaque Index, PLI;Biomarkers;Bleeding Index, BI;Alveolar Bone Loss Height;Alveolar bone loss percentage;Bone Defect Morphology;Bone Defect Width;Bone Defect Depth;Bone Defect Angle;Accuracy;Precision;Recall;F1?Score;ROC-AUC;Software usability;Diagnostic Time; | — |
Countries
China
Contacts
Public ContactWenjie Hu
Peking University Hospital of Stomatology
Outcome results
None listed