Upper limb dysfunction after stroke
Conditions
Interventions
Experimental Group 1:iTBS at M1 target plus action observation therapy
Experimental Group 2:iTBS at PMd target plus action observation therapy
Control group:sham iTBS plus action observation therapy
Sponsors
The Second Hospital of Jiaxing
Eligibility
Sex/Gender
All
Age
25 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.First-ever stroke onset, disease course ranging from 2 weeks to 3 months; 2.Aged 25–70 years old with stable vital signs and clinical condition; 3.Free from unilateral spatial neglect, hemianopia, as well as severe visual, auditory, cognitive and speech disorders; 4.Clear consciousness, capable of understanding and following instructions, with Mini-Mental State Examination (MMSE) score >= 24 points; 5.Ashworth scale grade of the affected upper limb <= grade 2; 6.All patients with right-sided hemiplegia, and able to tolerate treatment for no less than 2.5 hours per day;
Exclusion criteria
Exclusion criteria: 1.Recurrent stroke, obvious lesions or cerebral edema involving both cerebral hemispheres; 2.Complicated with myocardial infarction, angina pectoris, severe diseases of liver, kidney, lung, hematopoietic system, endocrine system, osteoarthropathy, malignant tumor and other complications limiting physical activity; 3.Subjects with previous history of mental illness, dementia, deafness or muteness; 4.Wounds, ulcers or severe infection on the hemiplegic limb skin; 5.Subluxation of shoulder joint, severe pain, numbness and other sensory disorders on the hemiplegic side; 6.Implanted electronic devices in the body such as cardiac pacemakers; 7.Implanted metallic substances in the body such as aneurysm clips;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Upper limb motor function;Upper limb functional activity ability;Activities of daily living; | — |
Secondary
| Measure | Time frame |
|---|---|
| Brain region activation and functional brain network connectivity; | — |
Countries
China
Contacts
Public ContactYa Sun
The Second Hospital of Jiaxing
Outcome results
None listed