Cognitive Impairment in Children with Cardiovascular Diseases
Conditions
Interventions
Control Group:Routine Treatment/Nursing Care
Intervention Group:Individualized Cognitive Digital Therapy + Routine Treatment/Nursing Care
Sponsors
Beijing Childrens Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
4 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1.Aged between 4 and 18 years; 2.Confirmed diagnosis of pediatric cardiovascular diseases (including congenital heart disease, arrhythmia, heart failure, pediatric hypertension, etc.) by an attending physician, meeting the corresponding diagnostic criteria. 3.Presence of cognitive function deficits, defined as at least one score below the norm (90 points) in the cognitive function assessment; 4.Good visual acuity or corrected visual acuity, able to complete digital assessments; 5.Fluent speech and normal communication ability; 6.Dominant hand function sufficient to complete tablet computer operations; 7.Written informed consent obtained from the child and their guardian(s).
Exclusion criteria
Exclusion criteria: 1.Presence of diseases that severely affect cognitive function: intellectual disability, intracranial tumors/space-occupying lesions, congenital or post-surgical brain tissue defects, encephalitis, ADHD, dementia, etc. 2.Severe mental disorders: schizophrenia, bipolar disorder, major depressive disorder, etc. 3.Presence of other congenital diseases; 4.Impaired function of major organs such as the liver, kidneys, or lungs; 5.Currently receiving or having received similar cognitive rehabilitation/training therapy within the past 3 months; 6.Poor adherence to assessments and interventions; 7.Incomplete clinical data; 8.Subjects judged by the researcher to require withdrawal or exclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive Function: Multi-dimensional Cognitive Assessment (Attention, Executive Function, Memory, Processing Speed, Perception); | — |
Secondary
| Measure | Time frame |
|---|---|
| Emotional and Behavioral Function: Scores on scales related to anxiety, depression, social anxiety, and attention;Clinical indicators of cardiovascular diseases: cardiac function classification, heart rate, blood pressure, oxygen saturation, central venous pressure, urine output, blood gas analysis, etc.;Safety and Adherence: Training completion rate and adverse events (eye fatigue, headache, irritability, etc.);Quality of Life: PedsQL 3.0 Cardiac Module (Child Self-Report + Parent Proxy Report); | — |
Countries
China
Contacts
Public ContactYanyan Xiao
Beijing Childrens Hospital,Capital Medical University
Outcome results
None listed