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A randomized controlled trial on the effectiveness of a sialic acid oligosaccharide-based agent in promoting hair regrowth in patients with chemotherapy induced alopecia

A randomized controlled trial on the effectiveness of a sialic acid oligosaccharide-based agent in promoting hair regrowth in patients with chemotherapy induced alopecia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600126664
Enrollment
Unknown
Registered
2026-06-12
Start date
2026-06-12
Completion date
Unknown
Last updated
2026-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chemotherapy induced alopecia

Interventions

Trial group (Sialo-OS ):The formulations will be applied topically to the scalp by subjects of the experimental respectively twice daily for 12 weeks.
Control group (placebo):The placebos will be applied topically to the scalp by subjects of the control groups respectively twice daily for 12 weeks.The placebo contains the extract of Tieguanyin tea,

Sponsors

Hong Kong Nang Yan College of Higher Education
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients with chemotherapy-induced alopecia (within 3 months post-chemotherapy); 2. Scalp alopecia covering at least 30% of the scalp area, and; 3. Willingness to provide informed consent and adhere to the study protocol. 4. Voluntarily sign the informed consent form and comply with the study protocol.

Exclusion criteria

Exclusion criteria: 1. Patients with other forms of alopecia (e.g., telogen effluvium, autoimmune diseases like lupus); 2. Scalp infections or dermatological conditions (e.g., psoriasis, eczema) that may interfere with hair regrowth; 3. Allergies to bird nest products or any ingredient in the formulation; 4. Use of other hair regrowth treatments (e.g., minoxidil, finasteride) within the past 3 months; 5. Use of other measures such as scalp cooling to prevent hair loss.

Design outcomes

Primary

MeasureTime frame
Hair density (number of hairs/cm2) ;Hair thickness;

Secondary

MeasureTime frame
Social Isolation;Appearance Anxiety;Body Image;

Countries

China

Contacts

Public ContactProf. Thomas WONG

Hong Kong Nang Yan College of Higher Education

thomaswong@ny.edu.hk+852 3996 1069

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 21, 2026