First-ever acquired brain injury (ischemic stroke, hemorrhagic stroke or traumatic brain injury) confirmed by CT/MRI
Conditions
Interventions
Experimental group:Multimodal brain visual training (integration of multisensory tasks in brain vision
visual fusion training
eye-controlled cognitive training), 5 times per week, 30 minutes each session, for 4 weeks
Control group:Traditional eye movement training (saccadic training, pursuit training, convergence training, and vestibulo-ocular reflex training), 5 times per week, 30 minutes each session, for 4 week
Sponsors
Beijing Bo'ai Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 75 years; 2. First-ever acquired brain injury (ischemic stroke, hemorrhagic stroke or traumatic brain injury) confirmed by CT or MRI; 3. Disease course ranging from 1 month to 12 months after onset; 4. Clinically diagnosed oculomotor dysfunction, including slow saccades, interrupted smooth pursuit, unstable fixation, reading difficulty and other related symptoms; 5. Stable vital signs, clear consciousness, and a Mini-Mental State Examination (MMSE) score of >= 17; 6. Able to cooperate with training and assessments, and willing to sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. There is a history of other neurological diseases such as Parkinson's disease, epilepsy and Alzheimer's disease in the past; 2. Severe visual impairment (uncorrected visual acuity < 0.1, still < 0.3 after correction) or organic eye diseases such as glaucoma, macular degeneration, and retinal detachment; Staring paralysis, visual field defects and nystagmus; 3. Severe aphasia and cognitive impairment, unable to understand training instructions; 4. Severe limb spasms, pain or orthostatic hypotension that affect sitting training; 5. Is currently participating in other clinical trials related to visual rehabilitation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NSUCO eye movement test;VP-measured fusion (base-in and base-out);Brain Vision oculomotor response time, completion time, and accuracy rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Reading Efficiency-Developmental Eye Movement Test;Visual Symptoms-Brain Injury Visual Symptom Survey;Quality of Life-National Eye Institute 25-Item Visual Functioning Questionnaire; | — |
Countries
China
Contacts
Public ContactLiu Dama
Beijing Bo'ai Hospital
Outcome results
None listed