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Exploration of endoscopic follow-up intervals after colon polypectomy: a non-inferiority target trial emulation

Exploration of endoscopic follow-up intervals after colon polypectomy: a non-inferiority target trial emulation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600126652
Enrollment
Unknown
Registered
2026-06-12
Start date
2026-06-12
Completion date
Unknown
Last updated
2026-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colonic polyps

Interventions

Strategy A:None
Strategy B:None

Sponsors

The first hospital of Shanxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. 50 years of age or older and 75 years of age or younger; 2. Never had a colonoscopy or undergone colonoscopic polypectomy prior to the first colonoscopy; 3. For a first-time colonoscopy, bowel preparation is adequate; the scope reaches the cecum; the withdrawal time exceeds 6 minutes; and the operator is satisfied. (A colonoscopy meeting the above criteria is defined as a high-quality colonoscopy. This definition is more practical than the USMSFT definition.); 4. A high-risk adenoma was identified during the initial colonoscopy and completely resected endoscopically. (High-risk adenoma is defined as: 3 to 10 non-advanced adenomas, or at least 1 advanced adenoma. The definition of high-risk adenoma used in this study differs slightly from that of the USMSTF: it excludes colorectal cancer and cases in which 11 or more adenomas were found.)

Exclusion criteria

Exclusion criteria: 1.History of familial adenomatous polyposis. 2.Medical history of Lynch syndrome. 3.History of inflammatory bowel disease. 4.History of colorectal cancer. 5.History of colorectal surgery. 6.The pathology of the polyps found during the first colonoscopy was inconclusive, making it impossible to determine whether they were high-risk adenomas. 7.More than 10 adenomas (excluding 10) were detected during the initial colonoscopy.

Design outcomes

Primary

MeasureTime frame
Detection rate of advanced neoplasia;

Secondary

MeasureTime frame
Colorectal cancer incidence;

Countries

China

Contacts

Public ContactRen Junjie

The first hospital of Shanxi Medical University

renjunjie1120@163.com+86 351 463 9753

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 21, 2026