Hepatocellular carcinoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion Criteria: 1. Patients diagnosed with liver cancer for the first time at our hospital, with no prior anti-tumor treatment; 2. Underwent radical resection (including surgical resection, radiofrequency ablation, or radiofrequency ablation combined with resection), and pathological confirmation of HCC after surgery; 3. Complete preoperative and postoperative examination data; 4. Followed up at our hospital for more than 2 years; 5. Patients in the postoperative adjuvant targeted therapy group must have used the medication for more than six months without interrupting treatment for over 3 months; 6. No severe adverse reactions to targeted or interventional therapy that forced treatment discontinuation; 7. Patients in the postoperative adjuvant therapy group did not receive any other anti-tumor treatments (including radiofrequency, surgery, radiotherapy, other drugs) before recurrence or metastasis, aside from targeted and interventional therapy.
Exclusion criteria
Exclusion criteria: Exclusion Criteria: 1. Patients with HCC who are not receiving first-time treatment; 2. Non-radical resection, tumor markers not turning negative within 2 months post-surgery, or postoperative exams indicating residual tumor; 3. Pathological diagnosis not consistent with HCC; 4. Postoperative adjuvant therapy includes treatments other than interventional or targeted drugs, or patients enrolled in other clinical studies; 5. Lost to follow-up post-surgery or missing hospital-recorded follow-up for more than six months; discontinued targeted drugs for over 3 months due to adverse reactions and postoperative adjuvant therapy was less than six months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of recurrence; | — |
Countries
China
Contacts
The First Affiliated Hospital of Xi'an Jiaotong University