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A single-center prospective randomized controlled study comparing the effects of low bacterial diet versus aseptic diet on infections in patients undergoing autologous hematopoietic stem cell transplantation

A single-center prospective randomized controlled study comparing the effects of low bacterial diet versus aseptic diet on infections in patients undergoing autologous hematopoietic stem cell transplantation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600126592
Enrollment
Unknown
Registered
2026-06-11
Start date
2026-06-15
Completion date
Unknown
Last updated
2026-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autologous hematopoietic stem cell transplantation

Interventions

low bacterial diet group:low bacterial diet
aseptic diet group:aseptic diet

Sponsors

Peking Union Medical College Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Autologous hematopoietic stem cell transplantation at the bone marrow transplant ward of Peking Union Medical College Hospital. 2.A unified preconditioning chemotherapy regimen was used for each disease before surgery; 3.Agree to participate in this study; 4.Age >= 18 years;

Exclusion criteria

Exclusion criteria: 1.Patients who are unable to eat orally; 2.Active infection already present before the onset of neutropenia; 3.Patients with gastrointestinal-related diseases;

Design outcomes

Primary

MeasureTime frame
Incidence of febrile neutropenia;

Secondary

MeasureTime frame
Days of diarrhea;Incidence of positive blood culture;Incidence of positive stool bacteriological examination;Incidence of diarrhea;Length of hospital stay;Percentage of body weight loss;Days of febrile neutropenia;

Countries

China

Contacts

Public ContactHui Ma

Peking Union Medical College Hospital

mahui3776@sina.com+86 10 6915 5623

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 21, 2026