Infertility ? Thin Endometrium
Conditions
Interventions
Control Group:none
Low-Concentration Group:Intrauterine infusion of platelet-rich plasma (low concentration)
Medium-Concentration Group:Intrauterine Perfusion with Platelet-Rich Plasma (medium concentration)
High-Concentration Group:Intrauterine Perfusion with Platelet-Rich Plasma(high concentration)
Sponsors
The Second Nanning People’s Hospital
Eligibility
Sex/Gender
Female
Age
No minimum to 40 Years
Inclusion criteria
Inclusion criteria: 1.Age <= 40 years. 2.Previous cancellation of embryo transfer due to an endometrial thickness of < 7 mm on the day of human chorionic gonadotropin (hCG) administration in a natural or ovulation induction cycle, or on the day of endometrial transformation in a hormone replacement cycle. 3.Normal uterine cavity confirmed by hysteroscopy. If intrauterine adhesions were present, they must have been completely lysed during the procedure, with no signs of recurrence on postoperative three-dimensional ultrasonography. 4.Normal thyroid function, blood glucose, and blood lipid profiles. 5.Infertility attributable mainly to pelvic/tubal factors, ovulatory dysfunction, or male factors, with no significant concurrent medical or surgical diseases.
Exclusion criteria
Exclusion criteria: 1.History of estrogen-related malignancies; 2.Abnormal uterine cavity on hysteroscopy (e.g., untreated submucosal uterine fibroids); 3.Endometrial pathologies, including but not limited to endometrial hyperplasia, endometrial tuberculosis, or untreated endometritis. 4.Adenomyosis; 5.Endometriosis of American Society for Reproductive Medicine (ASRM) stages III-IV. 6.Severe bilateral hydrosalpinx; 7.History of recurrent implantation failure; 8.Unavailability of cryopreserved blastocysts for transfer;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endometrial Thickness;Clinical Pregnancy Rate; | — |
Countries
China
Contacts
Public ContactHaitao Yang
The Second Nanning People’s Hospital
Outcome results
None listed