Aging
Conditions
Interventions
8-hour Time-restricted eating group:Daily eating window limited to 8 hours
Control group:Stick to your usual diet, eating for more than 8 hours.
Sponsors
Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age: Adults aged 18 years or older; 2. Body mass index (BMI): Between 18.5 and 24.0 kg/m^2; 3. Lifestyle: Sedentary lifestyle (engaging in less than 60 minutes of light physical activity per week during the previous 3 months), maintaining a normal sleep duration (7-9 hours per day), and having a habitual daily eating window exceeding 10 hours; 4. Health status: Free of acute or chronic diseases that may interfere with the study intervention and able to comply with study requirements; 5. Cognitive ability: Able to understand and agree to the study requirements, willing to provide written informed consent, and able to comply with dietary recording, physical examinations, and biological sample collection procedures; 6. Ability to use electronic devices: Able to use electronic devices (e.g., smartphones) to complete dietary records, daily check-ins, and communication with the research team.
Exclusion criteria
Exclusion criteria: 1. Current practice of time-restricted eating: Individuals who have independently followed an 8-hour or more restrictive time-restricted eating regimen during the previous 3 months; 2. Severe metabolic and chronic diseases: History of diabetes or hypoglycemia, metabolic disorders requiring special dietary management; cardiovascular diseases (e.g., myocardial infarction, stroke, or heart failure); chronic kidney disease or liver disease; current or previous malignant tumors; severe neurological or endocrine disorders; 3. Gastrointestinal diseases: Severe gastrointestinal disorders (e.g., peptic ulcer disease, inflammatory bowel disease, or gastroesophageal reflux disease) or a recent history of gastrointestinal surgery; 4. Severe psychological or psychiatric disorders: Diagnosed depression, anxiety disorder, schizophrenia, or other mental health conditions that may impair adherence to the intervention protocol; 5. Unhealthy lifestyle habits: Current smokers or individuals who consume alcohol more than twice per week; 6. Limited ability to comply with the study protocol: Individuals unable to maintain a relatively regular lifestyle or comply with the intervention requirements; unable to use electronic devices for dietary recording or communication with the research team; 7. Pregnant or breastfeeding women, or women planning to become pregnant during the study period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Klemera-Doubal Method Biological Age (KDM-BA);Phenotypic Age (PhenoAge); | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight;body temperature;gut microbiota;Blood indicators of liver and kidney function;Complete Blood Count;C-reactive protein, CRP;fasting blood glucose;Glycated hemoglobin (HbA1c);Total Cholesterol, TC; | — |
Countries
China
Contacts
Public ContactShi Dan
Chongqing Medical University
Outcome results
None listed