Vitiligo
Conditions
Interventions
Treatment Group C:Topical drugs +CAP thermosensitizer injection
Treatment Group B:Topical drug +CAP hydrogel
Treatment Group A:Topical drug group
Sponsors
Xi'an Jiaotong University Second Affiliated Hospital
Eligibility
Sex/Gender
All
Age
14 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. The age ranged from 14 to 65 years, both sexes; 2. The patient was diagnosed with vitiligo and met the criteria for advanced vitiligo according to the Chinese Journal of Dermatology Consensus on the Diagnosis and Treatment of Vitiligo (2021 edition); 3. The vital signs were stable; 4. Informed consent was signed by the subjects;
Exclusion criteria
Exclusion criteria: 1. Who had received systemic treatment with investigational drugs, biological agents, and immunosuppressive agents (glucocorticoids or small-molecule JAK inhibitors) within 4 weeks, and topical glucocorticoids, phototherapy, and other treatments within 2 weeks; 2. Patients with a history of serious systemic disease or malignancy; 3. Pregnant or lactating women; 4. Abnormal liver and kidney function (serum AST, ALT, CREA increased more than 2 times) or blood routine (WBC, RBC or PLT lower than 80% of normal value) in patients who were to be injected with CAP dosage form; 5. Other circumstances that the investigator deemed inappropriate for trial participation;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vitiligo Index Area Scoring; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient Satisfaction ratings;Dermatology Life Quality Index; | — |
Countries
China
Contacts
Public ContactXia Yumin
Xi'an Jiaotong University Second Affiliated Hospital
Outcome results
None listed