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Application Value of Autologous Blood Recovery Strategy in Obstetric Massive Hemorrhage Cesarean Section Based on Oxygen Metabolism Resuscitation Goals: A Mixed Cohort Study

Application Value of Autologous Blood Recovery Strategy in Obstetric Massive Hemorrhage Cesarean Section Based on Oxygen Metabolism Resuscitation Goals: A Mixed Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600126559
Enrollment
Unknown
Registered
2026-06-11
Start date
2026-06-15
Completion date
Unknown
Last updated
2026-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean section for massive hemorrhage

Interventions

IOCS Group:None

Sponsors

Meizhou People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18–45 years; 2. Undergoing cesarean section with intraoperative blood loss > 1000 mL; 3. Complete documentation of intraoperative blood loss; availability of intraoperative arterial blood gas analysis; traceable results of preoperative and postoperative routine coagulation tests (PT, APTT, INR, TT) and complete blood count (CBC); 4. IOCS group: Intraoperative use of autologous cell salvage (ACS) with the salvaged blood reinfused through a leukocyte depletion filter (LDF); 5. Conventional group: Patients with the same degree of blood loss during the same period but without the use of ACS.

Exclusion criteria

Exclusion criteria: 1. Patients who underwent concurrent surgery on other organs during the procedure that may affect the assessment of blood loss; 2. Patients who were transferred to our hospital for emergency cesarean section after examination at another hospital, with missing preoperative laboratory data in our hospital; 3. Patients in whom ACS + LDF was used during surgery but reinfusion was not performed due to equipment malfunction.

Design outcomes

Primary

MeasureTime frame
The rate of change in arterial oxygen content (CaO?);

Secondary

MeasureTime frame
Inflammation-Coagulation Restricted Index (ICI-R);Oxygenation index (OI);Lactate;Allogeneic blood transfusion volume;Length of stay (LOS) Hospital stay duration;

Countries

China

Contacts

Public ContactZhi Chen

Meizhou People's Hospital

86288976@qq.com+86 137 5055 8655

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 21, 2026