Pigmented Periorbital Dark Circles
Conditions
Interventions
Control group:Q-1064 nm Nd:YAG laser
Experimental group:730 nm Picosecond Laser
Sponsors
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18 to 60 years old (inclusive) with any gender; 2.Patients who was diagnosed with pigmented periorbital dark circles by two experienced physicians; 3.Patients who without any periorbital treatment within 3 months prior to treatment; 4.Patients who signed the informed consent form; 5.Patients who with Fitzpatrick Skin Type ?-?.
Exclusion criteria
Exclusion criteria: 1. Women during pregnancy and lactation; 2. Patients who with periorbital infection or obvious scars; 3. Patients who had a history of any bleeding or coagulation disorders with platelet count < 100×10?/L; 4. Patients who received periorbital cosmetic treatments such as chemical peeling, laser, radiofrequency therapy and injections in the past 3 months; 5. Patients who were allergic to Lidocaine; 6. Any periorbital hyperpigmentation caused by any clinical diseases and other vascular or structural factors; 7. Patients who with application of topical whitening agents within 14 day or photosensitive drugs within 30 days; 8. Patients with systemic hormone use.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effective Clearance Rate;Questionnaire Score of periorbital dark circles; | — |
Secondary
| Measure | Time frame |
|---|---|
| MASI Score of Infraorbital Hyperpigmentation Area;L?a?b? value of periorbital dark circles;Clearance rate of periorbital dark circles;Safety Assessment; | — |
Countries
China
Contacts
Public ContactMa Gang
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Outcome results
None listed