Ischemic Stroke
Conditions
Interventions
Individualized adjustment group:Cilostazol 100mg bid
No adjustment Group:Aspirin/Clopidogrel
Sponsors
Drum Tower Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years; 2.Ischemic stroke onset within 7 days; 3.On aspirin 100 mg qd or clopidogrel 75 mg qd for 5–7 days before platelet-function testing; 4.Able to comply with follow-up.
Exclusion criteria
Exclusion criteria: 1. Concurrent use of other anticoagulants, antiplatelet drugs, fibrinolytics, or other drugs affecting coagulation function; 2. Patients with an expected survival of less than 1 year for various reasons; 3. Contraindications to antithrombotic therapy, or allergy to related drugs; 4. Patients with severe heart, liver, or kidney dysfunction; 5. Participation in other clinical studies within the past 3 months; 6. Serum HIV positive; 7. Severe mental disorders, cognitive dysfunction, or inability to understand and sign the informed consent form; 8. Presence of coagulation dysfunction, active bleeding, or bleeding tendency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cerebral infarction, myocardial infarction and ischemic events;mortality rate; serious adverse events including intracranial and gastrointestinal hemorrhagic events; | — |
Secondary
| Measure | Time frame |
|---|---|
| Percentage of patients with a modified Rankin Scale (mRS) score <= 2 points;All adverse events;Barthel Index of activities of daily living, MMSE score and MoCA score; | — |
Countries
China
Contacts
Public ContactShao Tengfei
Drum Tower Hospital
Outcome results
None listed