Knee osteoarthritis
Conditions
Interventions
exposure group: IPFP signal abnormal group:NA
Non-exposure group: IPFP signal normal group:NA
Sponsors
Zhujiang Hospital, Southern Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 40-80 years, diagnosed with primary KOA, Kellgren-Lawrence (K-L) grade 1-3 (early-to-mid stage) 2. Completed 3.0T knee MRI examination in our hospital within 6 months before surgery, with complete imaging data 3. Underwent first-time ipsilateral standardized arthroscopic debridement (synovectomy, meniscectomy/partial meniscectomy, loose body removal, chondroplasty) 4. Complete postoperative follow-up data, minimum follow-up duration =5 years
Exclusion criteria
Exclusion criteria: 1. Secondary KOA (post-traumatic, rheumatoid, infectious, crystalline arthritis, etc.) 2. Preoperative K-L grade 4 or previous ipsilateral knee surgery history 3. Preoperative absolute indication for TKA 4. Severe lower limb alignment deformity (hip-knee-ankle angle >15°) 5. Incomplete follow-up data or inability to determine endpoint events 6. Complicated with malignant tumors, severe liver and kidney dysfunction or other major diseases affecting survival
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TKA-free Survival;5-Year Cumulative TKA Incidence Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| 5-Year Rate of Long-Term Oral Analgesic Dependence After Surgery;5-Year Radiographic Progression Rate of Knee Osteoarthritis (KOA) After Surgery; | — |
Countries
China
Contacts
Public ContactLijun Lin
Zhujiang Hospital, Southern Medical University
Outcome results
None listed