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A RCT of two laparoscopic staining anatomical liver resection for hepatocellular carcinoma

A RCT of laparoscopic hepatic artery staining fluorescence navigation (LPTAR) and portal vein traditional anatomical resection (HASLAR) for hepatocellular carcinoma

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600126534
Enrollment
Unknown
Registered
2026-06-10
Start date
2026-06-10
Completion date
Unknown
Last updated
2026-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma

Interventions

Hepatic artery staining laparoscopic anatomical resection:Laparoscopic portal vein traditional anatomical resection
Laparoscopic portal vein traditional anatomical resection:Laparoscopic portal vein traditional anatomical resection

Sponsors

The First Affiliated Hospital of Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-75 years; 2. General condition is good. The patient is ASA I-II grade, can tolerate pneumoperitoneum, and has no contraindications for laparoscopic surgery or DSA surgery; 3. Liver function is classified as Child-Pugh A or B, and the ICG retention rate 15 minutes before the operation (ICG-R15) is less than 10%, and the residual liver volume/standard liver volume is greater than 40%; 4. The maximum diameter of the tumor is <= 5 cm, and both are suitable for LPTAR and HASLAR; 5. The tumor meets the CNLC stage Ia; 6. The patient is not allergic to ICG and iodized oil.

Exclusion criteria

Exclusion criteria: 1. Non-anatomic liver resection (NAH); 2. Laparoscopic surgery without the use of ICG, including liver resection of other abdominal organs except for cholecystectomy, as well as preoperative anti-cancer treatments such as radiofrequency ablation, radiotherapy, and systemic chemotherapy other than TACE and DSA; 3. Postoperative pathology indicates metastatic liver cancer or primary liver cancer of other tissue types; 4. Previous or current coexistence of other malignant tumors in other parts; 5. Recurrent HCC requiring repeated liver resection; 6. Tumor rupture before the operation; 7. Conversion to open surgery; 8. Previous history of abdominal surgery.

Design outcomes

Primary

MeasureTime frame
3-year tumor-free survival rate after surgery;

Secondary

MeasureTime frame
Overall survival rate 3 years after surgery;Postoperative complications;

Countries

China

Contacts

Public ContactZheng Shuguo, Liao Kexi

The First Affiliated Hospital of Army Medical University

291909528@qq.com+86 23 6876 5706

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 21, 2026