Sepsis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Included patients were aged over 18 years and met the Sepsis-3 diagnostic criteria. Sepsis was defined as suspected infection with an acute increase of = 2 points in the Sequential Organ Failure Assessment (SOFA) score. For patients with multiple episodes of sepsis during the same hospitalization, only the data from the first diagnostic episode was retained for analysis. 2. Patients with an ICU stay longer than 24 hours were included. For patients with multiple ICU admissions, only the data from the first admission was analyzed.
Exclusion criteria
Exclusion criteria: 1.Pregnant or lactating women; 2.Severely missing clinical data (missing rate of core predictive variables > 30%); 3.Patients with a prior diagnosis of chronic kidney disease (CKD) stage 4–5 or a history of long-term renal replacement therapy; 4.Patients who withdrew treatment, were transferred to hospice care within 24 hours of ICU admission, or had an expected survival time of less than 72 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-day mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| 28-day RRT-free days;Precision;Accuracy;Recall;F1;area under the curve; | — |
Countries
China
Contacts
Affiliated Hospital of Guangdong Medical University