Respiratory dysfunction, cognitive dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Presence of respiratory dysfunction (defined as impaired gas exchange or ventilation capacity due to abnormalities of the lungs, airways, chest wall, or nervous system, manifested as dyspnea, hypoxia, or carbon dioxide retention.) 2.Adult patients aged 18–80 years. 3.Patients with stable medical condition and stable vital signs. 4.No olfactory dysfunction, and no allergic rhinitis during training or testing periods. 5.No severe hearing loss (greater than 61 dB HL). 6.Study participants or their legal guardians agree to participate in this trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients with severe cognitive impairment (MMSE score < 14 or S5Q score < 2) are not eligible to participate in this trial. 2.Patients who are intolerant or averse to olfactory stimulation. 3.Patients with an artificial airway whose cuff cannot be deflated. 4.Study participants or their legal guardians request withdrawal from the clinical trial. 5.Patients whose medical condition is still unstable with fluctuating vital signs. 6.Pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaphragm ultrasound parameters;Pulmonary function;Comprehensive respiratory function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Arterial blood gas (ABG) parameters;Six-minute walk distance (6MWD);Barthel Index;Montreal Cognitive Assessment (MoCA);Squire five questions(S5Q); | — |
Countries
China
Contacts
China-Japan Friendship Hospital