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Comparison of Taijilidine and Sufentanil on Propofol Requirements in Hysteroscopic Surgery: A Double-Blind, Dose-Response Study

Comparison of Taijilidine and Sufentanil on Propofol Requirements in Hysteroscopic Surgery: A Double-Blind, Dose-Response Study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600126493
Enrollment
Unknown
Registered
2026-06-10
Start date
2026-07-01
Completion date
Unknown
Last updated
2026-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecological diseases

Interventions

Group S:Intravenous infusion of 0.10 µg/kg of Sufentanil
Group A:Intravenous infusion of 0.75mg of Taijilidine
Group B:Intravenous infusion of 1.00mg of Taijilidine

Sponsors

Foshan Maternity & Child Healthcare Hospital,
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Patients scheduled for hysteroscopic surgery at Foshan Women and Children's Hospital; 2.American Society of Anesthesiologists (ASA) classification grades ? to ?; 3.Aged 18–60 years; 4.Mallampati class I or II; 5.Body mass index between 18 and 30 kg/m²; 6.Sign the informed consent form for the clinical trial;

Exclusion criteria

Exclusion criteria: 1.Allergy or contraindication to any drug used in this study; 2.Use of sedatives (midazolam, barbiturates), psychotropic drugs, or opioids within 7 days prior to surgery; 3.Presence of congenital uterine malformations; 4.Presence of severe cardiac, pulmonary, hepatic, or renal insufficiency; 5.Presence of psychiatric disorders that may interfere with cooperation in evaluation and follow-up; 6.Any condition deemed unsuitable for enrollment by the investigators;

Design outcomes

Primary

MeasureTime frame
Response to hysteroscopic examination;

Secondary

MeasureTime frame
Total propofol dose;NRS score;Recovery time;Perioperative adverse events;

Countries

China

Contacts

Public ContactYifei Chen

Foshan Maternity & Child Healthcare Hospital,

591467821@qq.com+86 10 0000 0000

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 21, 2026