Sarcopenia in the elderly with mild cognitive impairment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Elderly individuals aged 60 or above who reside in the community; 2. Diagnosed with sarcopenia combined with mild cognitive impairment; 3. Possess basic walking and independent activity abilities; 4. Without visual or auditory impairments, able to communicate normally; 5. Diagnostic criteria: (1) Conform to the 2018 "Chinese Guidelines for Diagnosis and Treatment of Dementia and Cognitive Impairment" and the diagnostic criteria proposed by Petersen et al.: have a complaint of memory decline for 3 months or more; mild impairment of daily living ability (16 points = 12 s; Short Physical Performance Battery (SPPB) <= 9 points; any one of the above conditions is met. Possible diagnostic criteria for sarcopenia: A or C, diagnostic criteria for sarcopenia: A+B or B+C; severe sarcopenia diagnostic criteria: A+B+C. To follow the concepts of early identification and early intervention of sarcopenia in the 2019 AWGS and 2025 AWGS guidelines, this study also includes community-dwelling elderly with possible sarcopenia and those diagnosed with sarcopenia; 6. Can use or can use a smartphone with the help of family members; 7. Informed consent, voluntarily participating in this study.
Exclusion criteria
Exclusion criteria: 1.Severe diseases such as acute exacerbation of chronic obstructive pulmonary disease, severe cardiovascular and cerebrovascular diseases (e.g., coronary heart disease with recurrent angina, acute cerebral infarction, cerebral hemorrhage, etc.), moderate to severe cognitive impairment, and uncontrolled mental disorders; 2.Neurological diseases that severely affect motor function (e.g., Parkinson's disease, severe limb dysfunction after stroke, etc.); 3. Severe organ dysfunction involving the heart, lungs, liver, kidneys, or other vital organs, or presence of contraindications to exercise (e.g., unstable angina, uncontrolled hypertension, recent fracture, etc.); 4.End-stage acute or chronic diseases (e.g., advanced malignant tumors) or infectious diseases (e.g., active pulmonary tuberculosis, etc.); 5. Severe hearing, visual, or speech impairments that prevent completion of cognitive tasks; 6.Currently participating in other exercise or cognitive intervention studies; 7.Unable to undergo bioelectrical impedance analysis (BIA) testing (e.g., due to implanted stents, pacemakers, artificial joints, etc.); 8.Physical disability, movement disorders, or inability to stand independently.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Muscle Strength (Grip Strength);Montreal Cognitive Assessment Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Short Physical Performance Assessment;Appendicular skeletal muscle mass index; | — |
Countries
China
Contacts
West Southwest Medical University Affiliated Hospital