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The influence of different fluid infusion volunes on central veins

study on the effects of different fluid replacement volumes on CVP invulnerable elderly patients undergoing gastrointestinal surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600126482
Enrollment
Unknown
Registered
2026-06-09
Start date
2025-04-02
Completion date
Unknown
Last updated
2026-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastrointestinal diseases in elderly patients

Interventions

experimental group:2.5 mL/kg of crystalloid solution was administered via the central venous access over 5 minutes each time.

Sponsors

The First People's Hospital of Fuyang
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Scheduled surgery; 2. Age: >= 65 years old; 3. mFI score >= 0.27 points; 4. ASA classification: I - III grades; 5. Body Mass Index (BMI) < 30 kg/m^2; 6. Require radial artery puncture and central venous catheterization; 7. CVP<5 cmH20 before fluid replacement; 8. Patients who have undergone intestinal preparation before surgery; 9. No unconscious functional disorder before surgery, and can cooperate quietly under spontaneous breathing.

Exclusion criteria

Exclusion criteria: 1. mFI score was less than 0.27 points; 2. Emergency surgery; 3. Patients who had undergone tracheal intubation and mechanical ventilation before the operation; 4. Acute respiratory failure (including acute exacerbation of COPD, acute lung injury or acute respiratory distress syndrome); 5. Patients with severe valvular heart disease; 6. patients with unstable hemodynamics or congestive heart failure (NYHA III-IV grade or GOLD III-IV grade) or persistent ventricular arrhythmia; 7. Sepsis or septic shock; 8. Moderate to severe liver and kidney dysfunction or those requiring renal replacement therapy (CRRT); 9. Pregnant or planning to have children; 10. Participating in other clinical intervention trials; 11. Refusing to participate in this study.

Design outcomes

Primary

MeasureTime frame
Central Venous Pressure (CVP);

Secondary

MeasureTime frame
blood oxygen saturation;heart rate;blood pressure;

Countries

China

Contacts

Public ContactYao Yan

The First People's Hospital of Fuyang

854546001@qq.com+86 139 6801 5459

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 21, 2026