Sleep disorder
Conditions
Interventions
Group B:Preoperative nasal spray of normal saline
Group A:Preoperative nasal spray of dexmedetomidine
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Ages 18 and older; 2.ASA I-III level; 3.Patients undergoing elective knee arthroscopy debridement; 4.Patients with preoperative sleep disorders(PSQI>5);
Exclusion criteria
Exclusion criteria: 1.Patients who refuse to provide informed consent form and refuse postoperative follow-up (including telephone follow-up after discharge); 2.Patients with contraindications or allergies to dexmedetomidine, general anesthetics, opioid drugs, or nonsteroidal drugs; 3.BMI below 19 or above 30 kg/m²; 4.Patient's medical history, such as preoperative heart rate less than 50 beats per minute; Sick sinus syndrome; Second degree or higher atrioventricular block; Left ventricular ejection fraction<50%; Individuals with previous obstructive sleep apnea syndrome; History of neurological, psychiatric, or mental health disorders; 5.Participants have participated in clinical trials of other drugs within the past 4 weeks; 6.Any situation that the researcher deems unsuitable for inclusion for any reason;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of sleep disorders on the first night after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of sleep disorders on the 2nd, 3rd, and 7th night after surgery;Postoperative nausea and vomiting incidence rate;Postoperative delirium incidence (0-24 hours);Anxiety and depression scores on postoperative days 1, 2, 3, and 7;Pain scores at rest and after activity 1 hour after surgery and on postoperative days 1, 2, 3, and 7; | — |
Countries
China
Contacts
Public ContactLuo Mengqiang
Huashan Hospital, Fudan University
Outcome results
None listed