High-grade serous ovarian carcinoma (HGSOC)
Conditions
Interventions
Disease group:None
Control Group:None
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: High-grade serous ovarian cancer (HGSOC) Inclusion Criteria: 1. Pathologically confirmed HGSOC; 2. Newly diagnosed patients who have not received any preoperative chemotherapy or radiotherapy; 3. Voluntarily participating in this study, with patients signing informed consent forms. Control Group Inclusion Criteria: 1. Patients undergoing hysterectomy or salpingectomy for benign gynecological diseases such as uterine fibroids or adenomyosis; 2. Normal fimbrial tissue of the fallopian tube confirmed by pathological examination to have no malignant lesions.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. Acute or chronic infectious diseases; 3. Autoimmune diseases; 4. Having a major surgical history or severe trauma history in the past 6 months; 5. Having cognitive impairments or mental disorders, and being unable to cooperate with the research process.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expression localization and intensity of PAX8, LDHA, HIF1A, and Pan-Kla proteins;Expression levels of FLNA, MYLK, ACTN1, and TAGLN proteins; | — |
Countries
China
Contacts
Public ContactLiandan Tang
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed